Drug-Induced Interstitial Lung Disease Essay

Drug-Induced Interstitial Lung Disease Essay

Drug-Induced Interstitial Lung Disease Essay

 what is Drug-Induced Interstitial Lung Disease

Don't use plagiarized sources. Get Your Custom Essay on
Drug-Induced Interstitial Lung Disease Essay
Just from $13/Page
Order Essay

Drug-Induced Interstitial Lung Disease
Drug-Induced Interstitial Lung Disease (DIILD) is a lung disease caused by exposure to a drug that causes inflammation and, ultimately, fibrosis of the lung interstitium. DIILD manifests with diverse clinical patterns, ranging from mild respiratory symptoms to rapidly progressive respiratory failure and death (Spagnolo et al., 2022). Most patients do not present with pathognomonic clinical, laboratory, radiological, or pathological features. Skeoch et al. (2018) explain that the clinical phenotype, imaging, and histopathology patterns differ significantly between drugs and between patients on the same drug. Thus, DIILD is a diagnosis of exclusion, which poses unique challenges for the treating physician. DIILD is usually suspected when there is exposure to a drug known to cause lung toxicity and after exclusion of alternative causes of Interstitial lung disease.


DIILD is graded using the National Cancer Institute Common Terminology Criteria for Adverse Events. Grade 1 (mild) is asymptomatic and only has radiographic findings. Grade 2 (moderate) is symptomatic but does not interfere with activities of daily living (Skeoch et al., 2018). Grade 3 (severe) is symptomatic and interferes with activities of daily living or oxygen indicated. Grade 4 is life-threatening or disabling and requires ventilator support, while grade 5 is fatal.
Patients likely to develop DILD include those receiving chemotherapy, those with rheumatoid arthritis and inflammatory bowel disease, and those receiving concurrent multiple toxic agents. The identified risk factors are: Age (extremes of age), sex (elderly females), dose, drug interaction, radiation, and underlying drug disease (Spagnolo et al., 2022). The drugs mostly associated with DILD include cytotoxic, anti-inflammatory, cardiovascular, antimicrobial, biological agents, and miscellaneous drugs.

Skeoch, S., Weatherley, N., Swift, A. J., Oldroyd, A., Johns, C., Hayton, C., Giollo, A., Wild, J. M., Waterton, J. C., Buch, M., Linton, K., Bruce, I. N., Leonard, C., Bianchi, S., & Chaudhuri, N. (2018). Drug-Induced Interstitial Lung Disease: A Systematic Review. Journal of clinical medicine, 7(10), 356. https://doi.org/10.3390/jcm7100356
Spagnolo, P., Bonniaud, P., Rossi, G., Sverzellati, N., & Cottin, V. (2022). Drug-induced interstitial lung disease. European Respiratory Journal, 60(4). DOI: 10.1183/13993003.02776-2021

Calculate the price
Make an order in advance and get the best price
Pages (550 words)
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
How it works
Receive a 100% original paper that will pass Turnitin from a top essay writing service
step 1
Upload your instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
Pro service tips
How to get the most out of your experience with Proscholarly
One writer throughout the entire course
If you like the writer, you can hire them again. Just copy & paste their ID on the order form ("Preferred Writer's ID" field). This way, your vocabulary will be uniform, and the writer will be aware of your needs.
The same paper from different writers
You can order essay or any other work from two different writers to choose the best one or give another version to a friend. This can be done through the add-on "Same paper from another writer."
Copy of sources used by the writer
Our college essay writers work with ScienceDirect and other databases. They can send you articles or materials used in PDF or through screenshots. Just tick the "Copy of sources" field on the order form.
See why 20k+ students have chosen us as their sole writing assistance provider
Check out the latest reviews and opinions submitted by real customers worldwide and make an informed decision.
The absolute best ! Thanks for great communication, quality papers, and amazing time delivery!
Customer 452467, November 14th, 2022
Great work, Thank you, will come back with more work
Customer 452441, November 11th, 2022
This was done very well. Thank you!
Customer 452441, November 11th, 2022
Good work. Will be placing another order tomorrow
Customer 452441, November 11th, 2022
Well researched paper. Excellent work
Customer 452441, November 11th, 2022
Very fond of the paper written. The topic chosen is defiantly trending at this time
Customer 452495, July 27th, 2023
Customer reviews in total
Current satisfaction rate
3 pages
Average paper length
Customers referred by a friend
15% OFF your first order
Use a coupon FIRST15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat