NURS 6630 MIDTERM & FINAL EXAM STUDY GUIDES NURS 6630 Midterm & Final Exam Study Guides

NURS 6630 MIDTERM & FINAL EXAM STUDY GUIDES

NURS 6630 MIDTERM EXAM STUDY GUIDE
 Non-compliant patients
 Neurotransmitters
 Gene Expression
 Cytochrome P450 Enzyme System
 Pharmacokinetics
 Mechanisms of receptors including:
o G-Protein linked receptors

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NURS 6630 Midterm & Final Exam Study Guides

o nicotine cholinergic
o serotonin
o dopamine
o norepinephrine
o D2 receptors
o glycine receptors
o ionotropic receptors
 Medications classifications – Full agonists, antagonists, partial agonist, and inverse agonists
 Therapeutics, side effects, dosing, use, and special populations for medications to treat
o Psychosis and schizophrenia
o bipolar disorders
o depression
o mania
o paranoid psychosis
o panic disorders
o fibromyalgia
o smoking cessation
o Parkinson’s disease
o anxiety. 6630 Midterm & Final Exam Study Guides.
o stress
o PTSD
 How to identify improvement in a patient following administration of medication
 System-based approaches to treatment
 MAO inhibitors
Stahl’s Essential Psychopharmacology
Chapter 1 – Chemical Neurotransmission
 Anatomical versus chemical basis of neurotransmission

 Signal transduction cascades
 Epigenetics
Chapter 2 – Transporters, receptors, and enzymes as targets of psychopharmacological drug action
 Neurotransmitter transportation as targets of drug action
 G-protein-linked receptors
 Enzymes as targets of psychotropic drugs
 Cytochrome P450 drug metabolizing enzymes as targets of psychotropic drugs
Chapter 3 – Ion channels as targets of psychopharmacological drug action
 Ligand-gated ion channels as targets of psychopharmacological drug action
 Voltage-sensitive ion channels as targets of psychopharmacological drug action
 Ion channels and neurotransmission. NURS 6630 Midterm & Final Exam Study Guides.
Chapter 4 – Psychosis and schizophrenia
 Symptom dimensions in schizophrenia
 Neurotransmitters and circuits in schizophrenia
 Neurodevelopment and genetics in schizophrenia
 Neuroimaging circuits in schizophrenia
Chapter 5 – Antipsychotic agents
 Conventional antipsychotics
 Atypical antipsychotics
 Links between antipsychotic binding properties and chemical actions
 Pharmacologic properties of individual antipsychotics: the pines, the dones, two pips and a rip plus more
 Antipsychotics in clinical practice. NURS 6630 Midterm & Final Exam Study Guides.
 Future treatments for schizophrenia
Chapter 6 – Mood disorders
 Description of mood disorders
 The bipolar spectrum
 Can unipolar depression be distinguished from bipolar depression?
 Are mood disorders progressive?
 Neurotransmitters and circuits in mood disorders
 Stress and depression
 Symptoms and circuits in depression
 Symptoms and circuits in mania. NURS 6630 Midterm & Final Exam Study Guides.
 Neuroimaging and mood disorders

Chapter 7 – Antidepressants
 General principles of antidepressant action
 Antidepressant classes
 Augmenting antidepressants
 How to choose an antidepressant
 Future treatments for mood disorders
Stahl’s Illustrated Guide – Anxiety, Stress, and PTSD
Chapter 4 – First line medications for PTSD
 Pharmacological Treatments
 SSRIs
Chapter 5 – Second-line, adjunct, and investigational medications for PTSD
 Second-line Medications
 Adjunct Medications. NURS 6630 Midterm & Final Exam Study Guides.
 Investigational Medications

NURS 6630 FINAL EXAM STUDY GUIDE
 Therapeutics, side effects, dosing, use, and special populations for medications to treat
o psychotic aggression
o psychotic behaviors
o psychosis and aggression
o impulsive symptoms
o ADHD
o mood disorders
o fibromyalgia
o chronic pain
o migraines
o shingles
o Alzheimer’s disease
o dementia
o PTSD
o Premenstrual dysphoric disorder (PDD)
o Irritable bowel syndrome
o diabetic peripheral neuropathic pain
o addictions
o smoking cessation
o Kleptomania. NURS 6630 Midterm & Final Exam Study Guides.
o Impulsive aggression
o Insomnia and sleep disorders
o
Stahl’s Essential Psychopharmacology
Chapter 10 – Chronic pain and its treatment
 What is pain?
 Neuropathic pain
 Descending spinal synapses in the dorsal horn and the treatment of chronic pain
 Targeting sensitized circuits in chronic pain conditions
 Targeting ancillary symptoms in fibromyalgia
Chapter 11 – Disorders of sleep and wakefulness and their treatment
 Neurobiology of sleep and wakefulness
 Insomnia and hypnotics. NURS 6630 Midterm & Final Exam Study Guides.
 Excessive daytime sleepiness (hypersomnia) and wake-promoting agents

Chapter 12 – Attention deficit hyperactivity disorder and its treatment
 Symptoms and circuits: ADHD as a disorder of the prefrontal cortex
 ADHD as a disorder of inefficient “tuning” of the prefrontal cortex by dopamine and norepinephrine
 Neurodevelopment and ADHA
 Treatment
Chapter 13 – Dementia and its treatment
 Causes, pathology, and clinical features of dementia
 Three stages of Alzheimer’s disease. NURS 6630 Midterm & Final Exam Study Guides.
 Targeting amyloid as a future disease-modifying treatment of Alzheimer’s disease
 Targeting glutamate
 Treatments for psychiatric and behavioral symptoms in dementia
 Other proposed targets for dementia
Chapter 14 – Impulsivity, compulsivity, and addiction
 Overview of impulsive-compulsive disorders
 Neurocircuitry and the impulsive-compulsive disorders
 Substance addictions
 Obesity as an impulsive-compulsive disorder
Stahl’s Illustrated Guide – Chronic Pain and Fibromyalgia
Chapter 5 – Pain drugs. NURS 6630 Midterm & Final Exam Study Guides.
Stahl’s Illustrated Guide – ADHA
Chapter 4 – ADHD treatments
Stahl’s Illustrated Guide – Substance Use and Impulsive Disorders
Chapter 10 – Disorders of impulsivity and compulsivity
Stahl’s Illustrated Guide – Violence
Chapter 3 – Treatment of violence and aggression
Pharmacological Interventions for ADHD
 Table B. KQ2: Long-term (>1 year) effectiveness of interventions for ADHD in people 6 years and older
 Pharmacological Interventions
Article

Clancy, C.M., Change, S., Slutsky, J., & Fox, S. (2011). Attention deficit hyperactivity disorder: Effectiveness of treatment in at-risk preschoolers; long-term effectiveness in all ages; and variability in prevalence, diagnosis, and treatment. Table B. KQ2: Long-term(>1 year) effectiveness of interventions for ADHD in people 6 years and older. NURS 6630 Midterm & Final Exam Study Guides.